This is the Sequential Resonation Machine, created by Joseph Casbarian:
According to the post at oddmusic.com, the machine is a kind of mashup of a sequencer and a pipe organ. Three MP3s on the site provide brief examples of what kinds of music it can make: MP3, Sorcerer’s Apprentice-style note accrual; MP3, eerie horror shuffle; MP3, dopey cartoon waddle. (Via makezine.com.)